Percutaneous Local Ablative Therapy for Hepatocellular Carcinoma

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Percutaneous Local Ablation Therapy for Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a prevalent disease in Asia and the second leading cause of cancer death in Hong Kong.1 Surgical resection is regarded as the curative treatment. However, only 20% to 30% of HCC patients are suitable surgical candidates.2,3 Over the years, various locoregional therapies have been employed for the treatment of unresectable HCC. These include the widely practised...

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A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma.

OBJECTIVE To compare the results of percutaneous local ablative therapy (PLAT) with surgical resection in the treatment of solitary and small hepatocellular carcinoma (HCC). SUMMARY BACKGROUND DATA PLAT is effective in small HCC. Whether it is as effective as surgical resection in the long-term survivals remains unknown. METHODS We conducted a prospective randomized trial on 180 patients wi...

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Local ablative treatments for hepatocellular carcinoma: An updated review

Ablative treatments currently represent the first-line option for the treatment of early stage unresectable hepatocellular carcinoma (HCC). Furthermore, they are effective as bridging/downstaging therapies before orthotopic liver transplantation. Contraindications based on size, number, and location of nodules are quite variable in literature and strictly dependent on local expertise. Among abl...

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Results of surgical and percutaneous ablative therapy for hepatocellular carcinoma in elderly patients

Results A cohort of 45 Child-Pugh class A or B patients was collected. Of these, twenty-seven underwent surgery (male/female, 22/5; mean age 70). For 18 cases transcatheter arterial embolization (TACE), radiofrequency ablation (RFA), and portal vein embolization (PVE) (male/female, 15/3; mean age 74) were indicated (see Figure 1). Twenty patients with hepatitis C infection, 7 with hepatitis B i...

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Percutaneous local ablation therapy in small hepatocellular carcinoma.

Periodic screening programs conducted in various countries, applying sonography and serum alfa-fetoprotein to patients with chronic liver disease, have identified numerous small hepatocellular carcinoma (HCC). Although surgical resection is generally preferred for curative ablation, the long-term survival rates following resection are no better than those following local ablation. Current local...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 2003

ISSN: 0003-4932

DOI: 10.1097/01.sla.0000048443.71734.bf